flumist age

FLUMIST QUADRIVALENT is a vaccine indicated for active immunization of persons 2-49 years of age for the prevention of influenza disease caused by influenza A subtype viruses and type B viruses contained in the vaccine. Compared with the inactivated-vaccine group, the FluMist group had 89.2% fewer cases of influenza A/H1N1, a strain for which the vaccine was well-matched, and 79.2% fewer cases of A/H3N2, which the vaccine did not match well, the report says.

FluMist Quadrivalent should not be administered to patients who have a severe allergy to eggs, those who have ever had a life-threatening reaction to an influenza vaccination, or those who are between 2 and 17 years of age and take aspirin or medicines containing aspirin. FLUMIST QUADRIVALENT is a vaccine that is sprayed into the nose to help protect against influenza. Get CIDRAP news and other free newsletters. She called the study "the pivotal trial" supporting the request. In equal numbers, children were randomly assigned to receive either FluMist or the injectable vaccine, and each participant also received a placebo version of the other vaccine (FluMist recipients received dummy injections, and injectable-vaccine recipients received a placebo dose of nasal spray). But among previously unvaccinated children, 3.8% of FluMist recipients aged 6 to 11 months had a wheezing episode within 42 days after their first vaccine dose, as compared with 2.1% of the same age-group among inactivated vaccine recipients (P=.076).

He said the study strengthens his general impression that the immune response to live attenuated flu vaccines varies with age. It can be used in people 2 through 49 years old. "But this gap in the knowledge will make it harder for policy makers.". It's quite definitive.". University of Minnesota. Treanor also commented that in the FluMist study, the flu attack rate of 8.6% in the inactivated-vaccine group is "a reminder that flu vaccines are not perfect in young kids.". Both differences were significant. Get your flu shot at Walgreens. Study included 16 countriesThe study involved 249 physcians' offices and clinics in 16 countries, with about half of the sites in the United States. FluMist Quadrivalent is approved for individuals 2 through 49 years of age. Unrestricted financial support provided by, CIDRAP - Center for Infectious Disease Research and PolicyOffice of the Vice President for Research, University of Minnesota, Minneapolis, MN. FLUMIST QUADRIVALENT is for intranasal administration only. Though 'definitive,' study lacked placebo groupTreanor, a veteran vaccine researcher and professor of medicine, microbiology, and immunology, commented, "I think one of the things about the study that's remarkable is how carefully done it was and its size. "However, enthusiasm for the vaccine must be tempered" by the signs of an increased risk of wheezing and of hospitalization in children less than 1 year old, they write. Everyone else needs only 1 dose each flu season. "It's hard to have a placebo group in a population where a vaccine is already recommended as a routine step," Treanor said. The AAP recommends inactivated trivalent (three-strain) or quadrivalent (four-strain) flu shots for all children, reserving FluMist for children who would otherwise not receive a flu vaccine, such as in cases of vaccine refusal, and for whom the vaccine is indicated—healthy children age 2 … For culture-confirmed flu cases, the attack rates were 5.0% for the FluMist group and 10.0% for the inactivated vaccine group. In the international trial conducted in the 2004-05 flu season, there were almost 55% fewer cases of flu in children who received FluMist than in those who received the conventional injectable vaccine, according to a report published in the Feb 15 New England Journal of Medicine (NEJM). "On the basis of our results, the risk-benefit ratio for live attenuated vaccine appears favorable among children 12 to 47 months of age who have no history of wheezing. Last month the Food and Drug Administration (FDA) approved a new formulation that requires refrigeration but not freezing. As for vaccine safety, 6.1% of FluMist recipients between 6 and 11 months old were hospitalized for any cause within 180 days after vaccination, versus 2.6% of children in that age range who received inactivated vaccine, a significant difference. FluMist, made by MedImmune Inc., based in Gaithersburg, Md., has been on the market since 2003, but demand for it has been hampered by a higher cost than conventional vaccine and by the requirement to keep it frozen during storage. FluMist was originally developed by Hunein "John" Maassab, Professor of Epidemiology at the University of Michigan School of Public Health in Ann Arbor, Michigan and later by Aviron, in Mountain View, California, under the sponsorship of the National Institutes of Health (NIH) in the mid-1990s. Protect yourself and your family every flu season with the latest influenza vaccine available at Walgreens. Both FluMist and the injectable vaccines used in the trial, made by Aventis Pasteur, contained the three virus strains recommended by the FDA for the 2004-05 season. For the active immunization of individuals 2-49 years of age against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine. There was no significant difference in hospitalization rates between the two groups overall.

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